10-12 October 2017
Boston, USA

Pre Conference Workshop
Tuesday October 10, 2017

13.00 - 16.00

Innovating Drug Delivery & Formulation of Dermatological Drugs

Workshop Leader: Braham Shroot, Dermatology Drug Development, Independent Consultant Workshop Leader: Marc Brown, Co-Founder & CSO, MedPharm

Ensure that your drug delivery platforms and formulation
approaches are a step ahead. This is your opportunity to gain
in-depth insights from a veteran in the field, with plenty of
actionable case studies to learn from.

Key topics to be discussed:

  • Normal and Diseased Skin – a moving target
  • There is no placebo in dermatology, only vehicles
  • In Vitro models of drug release and drug distribution
     – How predictable are they?
     – Drug physical parameters – Is there a set for optimal skin penetration?
     – How to determine Drug Strength?
  • The influence of vehicles
     – Potency
     – Patient compliance 
  • Analyzing manufacturing
     – Influence of scale-up from bench to pilot to plant on formulation 
  • Exploring novel formulation approaches
     – Encapsulation
     – Challenges for delivery of peptides and oligonucleotides
     – Driving innovation in dermatology delivery and formulation

Braham Shroot, Dermatology Drug Development, Independent Consultant

Braham Shroot

Dr Shroot has over 35 years hands-on experience in Drug Research and Development specializing in Skin disorders including  Acne, Rosacea, Psoriasis, Atopic Dermatitis Fungal Infections, Chronic Ulcers and novel Aesthetic Biologic Products. Dr Shroot currently is an R&D  consultant to Health Care Companies, with an focus on a wide range of acute and chronic skin disorders including rare diseases.

Marc Brown, Co-Founder & CSO, MedPharm

Marc Brown

Professor Marc Brown received his BSc(Hons) and PhD in Pharmaceutical Chemistry from Loughborough University. In 2006, after 14 years working as an academic at King’s College London (KCL) he took up a position as Chair of Pharmaceutics in the School of Pharmacy, University of Hertfordshire and has been subsequently awarded Honorary Professorial positions at the School of Pharmacy, University of Reading and the Institute of Pharmaceutical Sciences, King’s College London. His research interests lie mainly in drug delivery to the skin, nail and mucosal membranes and he has over 200 publications and 25 inventions describing his work.

In 1998 whilst at KCL,  Professor Brown co-founded MedPharm Ltd,  a contract research organisation specialising in the development of topical and transdermal medicines. He acts as Chief Scientific Officer of MedPharm which employs ca. 140 people in its GMP/GLP accredited facilities in the UK and the US. Prof Brown has been involved in the development of 38 topical and transdermal medicines and devices that have gained regulatory approval around the world. These include two generic topical products that were approved in the EU based on MedPharm’s validated in vitro and ex vivo performance testing models.