Harnessing Immunomodulation to Transform Atopic Dermatitis & Beyond
- Immune mediation may result in complex dermatologic pathologies
- Immunomodulating, specifically focusing on T cells, may positively contribute to disease management
- Targeting the OX40 pathway in dermatology, eg atopic dermatitis, may result in sustained changes, representing remission (with case studies)
- Designing biologics with extended dosing intervals and low immunogenicity to reduce treatment burden and improve adherence
- Translational strategies are able to bridge mechanistic understanding to clinic-ready molecules that balance potency, safety, and patient convenience