Leveraging mTOR Inhibition to Restore Keratinocyte Homeostasis Across Rare Monogenic Skin Disorders
- Identifying shared pathological mechanisms across monogenic keratin disorders through translational research and patient-derived models
- Evaluating mTOR inhibition as a strategy to restore cellular homeostasis and improve disease outcomes across genetically distinct indications
- Leveraging cross-indication biology to create scalable development pathways in ultra-rare dermatology populations