Jeremy Bost, Ph.D.
Head of Clinical Affairs Ascilion AB
Seminars
Wednesday 4th November 2026
Dermal Interstitial Fluid as an Established Matrix for Local & Systemic Biology
12:00 pm
- Dermal interstitial fluid (dISF) is a valuable sample matrix for investigating both local tissue biology and systemic molecular dynamics, opening new opportunities for pharmaceutical research. Historically, dISF adoption has been limited by sample volume recovery, accessibility, and reproducibility
- Ascilion's PELSA system enables well-tolerated and reproducible collection of dISF for molecular analysis through minimally invasive hollow microneedle technology. PELSA is currently used in 35+ clinical studies across the EU and US within academic, cosmetics, and pharma development settings
- This presentation highlights real-world dISF data in tissue pharmacokinetics, inflammatory biomarker profiling, and longitudinal monitoring of biological responses
