Karl Beutner
Seminars
Thursday 20th November 2025
Rethinking Rare Dermatology: Advancing Topical & Systemic Innovation in Gorlin Syndrome and Dystrophic EB
1:00 pm
- Comparing topical and systemic strategies for treating rare dermatologic diseases
- Highlighting unmet systemic needs and treatment limitations in dystrophic EB
- Showcasing progress in managing basal cell carcinoma burden in Gorlin syndrome
- Sharing expanded data and previewing pipeline growth and potential acquisition news
Wednesday 19th November 2025
Panel Discussion: Can Topical and Systemic Therapies Each Find Their Place in the Future of Dermatology Drug Development?
4:30 pm
- How should we balance the clinical and commercial drivers behind topical and systemic innovation, especially as realworld prescribing habits continue to favor topicals? How are these approaches viewed from the patient, regulator and investor perspective?
- Which factors, including disease severity, body surface area, and treatment setting, best guide whether a topical, systemic, or combination approach is most appropriate? How can we best utilize both routes to ensure there is a treatment fit for everyone?
- How are both approaches evolving to better meet patient needs, from systemics tackling severe or widespread disease to topicals aiming for convenience, safety, or even disease modification?
- What are the key trade-offs between topical and systemic treatments in terms of patient adherence, cost, quality of life, and long-term disease control and how can trials be designed to reflect this?
