Karl Koehler
Associate Professor & Head of Neck Surgery & Otolaryngology, Department of Dermatology, Harvard Medical School
Seminars
Wednesday 4th November 2026
Building Predictive Human-Relevant Skin Models to Improve Translational Confidence & Accelerate First-in- Human Readiness
11:00 am
- Developing ex vivo, in vitro and chip-based skin models, improving human relevance, to strengthen confidence before clinical translation
- Testing emerging modalities in engineered model systems, capturing delivery, target engagement and tissue response, to reduce uncertainty before dose selection
- Learning from model innovation to benchmark advanced platform approaches, and improve preclinical decision-making across difficult dermatology questions
