Building Predictive Human-Relevant Skin Models to Improve Translational Confidence & Accelerate First-in- Human Readiness

  • Developing ex vivo, in vitro and chip-based skin models, improving human relevance, to strengthen confidence before clinical translation
  • Testing emerging modalities in engineered model systems, capturing delivery, target engagement and tissue response, to reduce uncertainty before dose selection
  • Learning from model innovation to benchmark advanced platform approaches, and improve preclinical decision-making across difficult dermatology questions