Pre-Conference Seminar Day 2023

Tuesday, October 31

8:00 am Coffee & Badge Collection

Synopsis

Join us for light refreshments and morning networking

“The Year of the JAK Inhibitor” – Your A-Z of JAK Inhibitors

8:55 am Chair’s Opening Remarks

Identifying Areas of Unmet Need to Examine Additional Applications of JAK Inhibitors

9:00 am Utilising JAK Inhibitors in Identifying Areas of Unmet Needs that have the Potential to be Served

  • Rob Ortmann Vice President, Clinical Development, Aclaris

Synopsis

  • Exploring Aclaris’ current success of JAKi in Atopic Dermatitis
  • Identifying the sub populations of patients within treated diseases that either are not well served and explore whether inhibition poses therapeutic possibilities
  • Looking forward what are the next therapeutic opportunities with JAK

9:30 am Roundtable Discussion: Identifying Where Future Opportunities Lies Whether Topical or Oral, Rare or Prevalent

Synopsis

This interactive session gives you the opportunity to be part of the discussion, get ready to share ideas and learn from your peers. Amongst your tables talking points to consider include:

  • With an increased appreciation of the applications of JAKi where do we see future opportunity.
  • Is there any reason why JAKi can’t become the drug of the future?
  • Does commercial success lie more with oral JAKis or with topical JAKis?

10:00 am Morning Break

Navigating Safety & Tolerability Challenges When Developing JAK Inhibitors

11:00 am Finding the Middle Ground Between Safety & Efficacy in Drug Development

  • Paul Smith Senior Vice President of Biology, Recludix

Synopsis

  • Identifying the risks associated with using JAK inhibitors and their likelihood of occurring
  • Contextualizing risk in terms of efficacy, finding the balance between effective treatment and safety, where is our limit?

11:30 am Interrogating the Safety & Efficacy Profile of JAK1 Selective Inhibitors in Inflammatory Disorders to Apply Learnings to the Skin

Synopsis

  • What can we learn from advances of JAK inhibitors in alternative indications?
  • Investigating mechanistic data and early clinical trial biomarker data to assess efficacy and safety of JAK1 inhibitors
  • Navigating clinical decision making and illuminating opportunities for indication expansion in inflammatory disorders

12:00 pm Lunch Break & Networking

Redefining the Gold Standard of JAK Inhibitors to Visualize the Next Generation

1:30 pm Roundtable: Visualizing the Next Generation of JAK Inhibitors to Transform the Dermatology Landscape

Synopsis

This interactive session gives you the opportunity to be part of the discussion, get ready to share ideas and learn from your peers. Amongst your tables talking points to consider include:

  • Identifying areas for improvement to visualize where progress will come from.
  • Explore if progress will come from a better safety profile, increased efficacy, a greater number of applicable diseases or a greater diversity of appropriate patients?
  • Discuss achievable and timely goals, to identify what good looks like so we can go after it.

2:00 pm Q&A Panel: Exploring the Evolution of the JAK Inhibitor Landscape

  • Paul Smith Senior Vice President of Biology, Recludix
  • Humberto Antunes Partner, Gore Range Capital & Former Chief Executive Officer, Galderma
  • John Armstrong President, JAV & Former Head of Discovery & Global Strategic Programs, Galderma

Synopsis

Explore the evolution of the JAK landscape and contextualize this in terms of future opportunities. This will be your opportunity to ask our expert speakers your pressing questions.

2:30 pm Chair’s Closing Remarks

2:35 pm End of Pre-Conference Workshop Day